New approaches to transplantation in acute myelogenous leukemia
نویسندگان
چکیده
منابع مشابه
New approaches to the treatment of chronic myelogenous leukemia.
A number of therapeutic strategies have been introduced for the management and treatment of the benign phase of CML. Eighty years ago, radiation therapy was the only available treatment and splenic ir~ radiation was continued for a period in ex~ cess of 20 years when in 1924, Minot and colleagues published the now classic paper demonstrating that, although therapy could reduce morbidity of the ...
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Acute myelogenous leukemia (AML) is a hematological malignancy, which accounts for about 15-25% of childhood's leukemia. Genetic factor is one of the most important predisposing elements in childhood acute leukemia, especially AML. In this case report, a rare presentation of familial AML is presented in three monozygotic triplets. Two were 10 months old, and the other one was 16 months old at p...
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From 2000 some data relative to IM resistance were available. There are many mechanisms responsible of IM resistance, more often point mutations that cause the progression to blast crisis and death in few months. To circumvent them, more potent TKIs have been subsequently approved [3]. However, another problem arise: these compounds don’t work on all patients because of the different IMresistan...
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Documented central nervous system (CNS) involvement in acute myelogenous leukemia (AML), unlike acute lymphocytic leukemia, is relatively uncommon [1 , 2] . CNS involvement in AML is reported to occur in 6%-17% of cases [1-4]. It is expected that improvements in therapy with increased frequency of remission and prolonged survival will lead to further increases in clinical CNS involvement in AML...
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ژورنال
عنوان ژورنال: Hematology
سال: 2015
ISSN: 1520-4391,1520-4383
DOI: 10.1182/asheducation-2015.1.596